Extracts from skin and seeds of Grapes (Vitis vinifera L., widely spread vine, originally from mediterranean area), are extremely rich in antioxidant compounds such as different oligomers of procyanidol, catechins, epichatechins, PAC, and other polyphenols like anthocyanins, flavanols, flavonols and resveratrol. This phytocomplex makes extracts of seeds and skins containing it indicated for prevention and tratment of several conditions related to vascular health (varicose veins, lymphedema, capillar fragility) and to promote vascular tone and elasticity, finally protecting from atherosclerosis.

These molecules are able to reduce oxidative damage, support microcirculation and improve vascular flexibility by a NO-mediated action; furthermore they reduce local inflammation and platelet aggregation. Health applications are related to cardiovascular, skin, eyes and cognitive health.